Global Albumin Usage in 2023 & Forecast to 2032

an analysis of the GLOBAL albumin MARKET IN 2023/24
AND FORECAST TO THE YEAR 2032
Albumin is the second most important plasma protein by sales, after immunoglobulins, and has been one of the two last liter products as it was made from which every plasma liter fractionated. It is also the most globalized protein, meaning a broader distribution of sales across countries and regions than any other plasma protein. Global sales of albumin for human therapeutic use were over $5 billion in 2022.
However, with recent changes in China, will this continue to be a last liter product for all liters fractionated? If not, then excess albumin would be expected, which would affect the price as well as the gross margins of all plasma companies. This question is addressed in this report, along with other questions such as: How is albumin used in western countries (North America and Europe) compared to albumin’s usage in eastern countries (China and Asia)? Where will albumin usage grow the fastest, and what is forecast to happen in China, the world’s largest albumin market? Will China albumin demand grow in the future, or face a slow decline, or something else? How will recombinant albumin impact the plasma derived albumin market in China? In mature markets in Europe, will albumin grow, and if so, how fast? How will the price of albumin change on an annual basis, especially if China doesn’t grow? These questions and more are answered in this new updated report, based on late 2025 market information from China and other countries.
This new report takes a deep look at current albumin usage around the globe, and details how albumin is used by medical specialty and key indications across all five geographic regions (North America, Europe, Asia/Pacific, Middle East/Africa and Latin America,). MRB’s forecast model analyzes both key drivers of albumin growth and how these trends will effect future growth, taking into account how the interaction of plasma supply and albumin demand can be expected to influence price patterns globally over the next 7 years. This report identifies albumin usage in over 100 countries in 2023 and 2024. Assumptions used to forecast albumin unit volume and pricing are based on (1) actual MRB sales data collected in 100 countries globally, (2) expert opinions on albumin usage across all five regions, (3) MRB’s analysis of future demographic and disease trends which affect albumin demand plasma supply, and (4) plasma supply and albumin pricing dynamics.
See the complete Table of Contents below for more details about the contents of this report.
TABLE OF CONTENTS
EXECUTIVE SUMMARY 5
- INTRODUCTION 17
Discovery of Human Albumin and the Beginning of the Plasma Fractionation Industry 17
Human Albumin and Plasma Economics over the Decades 18
Human Albumin for Non-therapeutic Applications 19
History of Albumin Demand and Price 20
Overview of the Clinical Use of Albumin 22
- FORECAST ASSUMPTIONS FOR PLASMA DERIVED ALBUMIN 26
- NORTH AMERICA ALBUMIN USAGE & FORECAST 32
2024 Albumin Usage in North America 32
2013 Analysis of Albumin Usage by Indication in North America 33
Current Albumin Usage by Indication in the United States 36
Cardiovascular Disease/Circulatory System Albumin Usage 37
Infectious Diseases (Sepsis) and Albumin Usage 37
Digestive System Diseases (Cirrhosis) Albumin Usage 38
Genitourinary Diseases (Kidney Failure) Albumin Usage 41
Cancer Albumin Usage 42
Trauma (injuries, burns, etc.) Albumin Usage 42
Other Diseases with Albumin Usage 44
Selective Publications Regarding Albumin Usage in North America 44
Forecast to 2032 in North America 54
Growth Drivers of Albumin Usage over the Forecast Period 56
Sales in Dollars and Price Expectations to 2032 64
- EUROPE ALBUMIN USAGE & FORECAST 66
2024 Albumin Usage in Europe 66
Current Albumin Usage by Indication in Europe 70
Selected Publications Reporting Albumin Clinical Trials in Europe 78
Forecast to 2032 in Europe 86
Growth Drivers of Albumin Usage over the Forecast Period 91
Sales in Dollars and Price Expectations to 2032 97
- ASIA AND PACIFIC ALBUMIN USAGE & FORECAST 99
2024 Albumin Usage in Asia & Pacific 99
China Albumin Usage in 2024 and 2025 101
Chinese Demand Decline in Albumin in 2025 102
Current Albumin Usage by Indication in Asia & Pacific 107
Current albumin Usage by Indications in China 107
Albumin Usage by Indication in other Asia & Pacific countries 108
Selective Publications Regarding Albumin Usage in Asia Pacific 109
China 109
Other Asia & Pacific countries 113
Forecast to 2032 in Asia & Pacific 117
China Forecast to 2032 126
Recombinant Albumin’s effect on China albumin market through 2032 132
Major changes between present forecast & the previous MRB forecast from 2024 137
- MIDDLE EAST AND AFRICA ALBUMIN USAGE & FORECAST 139
2024 Albumin Usage in Middle East & Africa 139
Current Albumin Usage by Indication in Middle East & Africa 141
Forecast to 2032 in Middle East & Africa 150
Growth Drivers of Albumin Usage over the Forecast Period 155
Sales in Dollars and Price Expectations to 2032 159
- LATIN AMERICA ALBUMIN USAGE & FORECAST 161
2024 Albumin Usage in Latin America 161
Current Albumin Usage by Indication in Latin America 162
Forecast to 2032 in Latin America 167
Growth Drivers of Albumin Usage over the Forecast Period 171
Sales in Dollars and Price Expectations to 2032 174
- WORLDWIDE ALBUMIN USAGE & FORECAST 176
2024 Global Albumin Usage 176
Global Albumin Forecast from 2024 to 2032 182
Yearly Growth in Units, Pricing and dollars 182
2032 Global Albumin Usage 185
Major changes between present forecast and the previous MRB forecast from 2024 187
Underlying Global Albumin Growth Drivers 189
Implications of Global Albumin Demand vs Potential Supply: Last Liter Impact 190