Global Albumin Usage in 2023 & Forecast to 2032

 

an analysis of the GLOBAL albumin MARKET IN 2023/24
AND FORECAST TO THE YEAR 2032

Albumin is the second most important plasma protein by sales, after immunoglobulins, and has been one of the two last liter products as it was made from which every plasma liter fractionated. It is also the most globalized protein, meaning a broader distribution of sales across countries and regions than any other plasma protein. Global sales of albumin for human therapeutic use were over $5 billion in 2022.

However, with recent changes in China, will this continue to be a last liter product for all liters fractionated? If not, then excess albumin would be expected, which would affect the price as well as the gross margins of all plasma companies. This question is addressed in this report, along with other questions such as: How is albumin used in western countries (North America and Europe) compared to albumin’s usage in eastern countries (China and Asia)? Where will albumin usage grow the fastest, and what is forecast to happen in China, the world’s largest albumin market? Will China albumin demand grow in the future, or face a slow decline, or something else? How will recombinant albumin impact the plasma derived albumin market in China? In mature markets in Europe, will albumin grow, and if so, how fast? How will the price of albumin change on an annual basis, especially if China doesn’t grow? These questions and more are answered in this new updated report, based on late 2025 market information from China and other countries.

This new report takes a deep look at current albumin usage around the globe, and details how albumin is used by medical specialty and key indications across all five geographic regions (North America, Europe, Asia/Pacific, Middle East/Africa and Latin America,).  MRB’s forecast model analyzes both key drivers of albumin growth and how these trends will effect future growth, taking into account how the interaction of plasma supply and albumin demand can be expected to influence price patterns globally over the next 7 years. This report identifies albumin usage in over 100 countries in 2023 and 2024. Assumptions used to forecast albumin unit volume and pricing are based on (1) actual MRB sales data collected in 100 countries globally, (2) expert opinions on albumin usage across all five regions, (3) MRB’s analysis of future demographic and disease trends which affect albumin demand plasma supply, and (4) plasma supply and albumin pricing dynamics.

See the complete Table of Contents below for more details about the contents of this report.

TABLE OF CONTENTS

EXECUTIVE SUMMARY                                                                 5

 

  1. INTRODUCTION                      17

Discovery of Human Albumin and the Beginning of the Plasma Fractionation Industry        17

Human Albumin and Plasma Economics over the Decades           18

Human Albumin for Non-therapeutic Applications                       19

History of Albumin Demand and Price                                          20

Overview of the Clinical Use of Albumin                                      22

 

  1. FORECAST ASSUMPTIONS FOR PLASMA DERIVED ALBUMIN                 26

 

  1. NORTH AMERICA ALBUMIN USAGE & FORECAST                    32

2024 Albumin Usage in North America                                         32

2013 Analysis of Albumin Usage by Indication in North America               33

Current Albumin Usage by Indication in the United States           36

Cardiovascular Disease/Circulatory System Albumin Usage        37

Infectious Diseases (Sepsis) and Albumin Usage                           37

Digestive System Diseases (Cirrhosis) Albumin Usage                 38

Genitourinary Diseases (Kidney Failure) Albumin Usage             41

Cancer Albumin Usage                                                                   42

Trauma (injuries, burns, etc.) Albumin Usage                                42

Other Diseases with Albumin Usage                                              44

Selective Publications Regarding Albumin Usage in North America                  44

Forecast to 2032 in North America                                                 54

Growth Drivers of Albumin Usage over the Forecast Period         56

Sales in Dollars and Price Expectations to 2032                            64

 

  1. EUROPE ALBUMIN USAGE & FORECAST                                66

2024 Albumin Usage in Europe                                                      66

Current Albumin Usage by Indication in Europe                           70

Selected Publications Reporting Albumin Clinical Trials in Europe             78

Forecast to 2032 in Europe                                                             86

Growth Drivers of Albumin Usage over the Forecast Period         91

Sales in Dollars and Price Expectations to 2032                            97

 

  1. ASIA AND PACIFIC ALBUMIN USAGE & FORECAST        99

2024 Albumin Usage in Asia & Pacific                                          99

China Albumin Usage in 2024 and 2025                                      101

Chinese Demand Decline in Albumin in 2025                             102

Current Albumin Usage by Indication in Asia & Pacific             107

Current albumin Usage by Indications in China                           107

Albumin Usage by Indication in other Asia & Pacific countries 108

Selective Publications Regarding Albumin Usage in Asia Pacific       109

China                                                                                             109

Other Asia & Pacific countries                                                     113

Forecast to 2032 in Asia & Pacific                                               117

China Forecast to 2032                                                                 126

Recombinant Albumin’s effect on China albumin market through 2032               132

Major changes between present forecast & the previous MRB forecast from 2024           137

 

  1. MIDDLE EAST AND AFRICA ALBUMIN USAGE & FORECAST       139

2024 Albumin Usage in Middle East & Africa                            139

Current Albumin Usage by Indication in Middle East & Africa  141

Forecast to 2032 in Middle East & Africa                                    150

Growth Drivers of Albumin Usage over the Forecast Period       155

Sales in Dollars and Price Expectations to 2032                          159

 

  1. LATIN AMERICA ALBUMIN USAGE & FORECAST          161

2024 Albumin Usage in Latin America                                        161

Current Albumin Usage by Indication in Latin America             162

Forecast to 2032 in Latin America                                                167

Growth Drivers of Albumin Usage over the Forecast Period       171

Sales in Dollars and Price Expectations to 2032                          174

 

  1. WORLDWIDE ALBUMIN USAGE & FORECAST             176

2024 Global Albumin Usage                                                        176

Global Albumin Forecast from 2024 to 2032                               182

Yearly Growth in Units, Pricing and dollars                                182

2032 Global Albumin Usage                                                        185

Major changes between present forecast and the previous MRB forecast from 2024        187

Underlying Global Albumin Growth Drivers                               189

Implications of Global Albumin Demand vs Potential Supply: Last Liter Impact         190